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SEE FULL PRESCRIBING INFORMATION FOR COMPLETE BOXED WARNING.
- Fentanyl Citrate Injection exposes users to risks of addiction, abuse, and misuse, which can lead to overdose and death. Assess patient’s risk before prescribing and monitor regularly for these behaviors and conditions
- Serious, life-threatening, or fatal respiratory depression may occur. Monitor closely, especially upon initiation or following a dose increase.
- Concomitant use with CYP3A4 inhibitors (or discontinuation of CYP3A4 inducers) can result in a fatal overdose of fentanyl.
- Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing for use in patients for whom alternative treatment options are inadequate; limit dosages and durations to the minimum required; and follow patients for signs and symptoms of respiratory depression and sedation.
DOSAGE AND ADMINISTRATION OF FENTANYL INJECTION
- Fentanyl Citrate Injection should be administered only by persons specifically trained in the use of intravenous anesthetics and management of the respiratory effects of potent opioids.
- Ensure that an opioid antagonist, resuscitative and intubation equipment, and oxygen are readily available.
- Individualize dosing based on the factors such as age, body weight, physical status, underlying pathological condition, use of other drugs, type of anesthesia to be used, and the surgical procedure involved.
- Initiate treatment in adults with 50 to 100 mcg (0.05 to 0.1 mg) (1 to 2 mL)
- Initiate treatment in children 2 to 12 years of age, with a reduced dose as low as 2 to 3 mcg/kg.
50-100mcg per kg or 1-2ml per kg. The doctor can administer it with oxygen and a muscle relaxant. In cases like complicated neurological, open-heart surgery, or orthopedic procedures, doses of up to 150mcg/kg or 3ml per kg can be required. It is wise to reduce the dose in the cases of debilitated or the elderly.
Note that children below two years should not take this drug. The induction and maintenance dose for those who are 2-12 years is 2-3mcg per kg
SIDE EFFECTS of Fentanyl Injection
The following serious adverse reactions are described, or described in greater detail, in other sections:
- Addiction, Abuse, and Misuse [see WARNINGS AND PRECAUTIONS]
- Life-Threatening Respiratory Depression [see WARNINGS AND PRECAUTIONS]
- Interactions with Benzodiazepines or Other CNS Depressants [see WARNINGS AND PRECAUTIONS]
- Serotonin Syndrome [see WARNINGS AND PRECAUTIONS]
- Severe Cardiovascular Depression [see WARNINGS AND PRECAUTIONS]
- Gastrointestinal Adverse Reactions [see WARNINGS AND PRECAUTIONS]
- Seizures [see WARNINGS AND PRECAUTIONS]
Is fentanyl stronger than morphine
Duragesic was first approved by the College ter Beoordeling van Geneesmiddelen, the Medicines Evaluation Board in the Netherlands, on July 17, 1995, as 25, 50, 75 and 100 µg/h formulations after a set of successful clinical trials, and on October 27, 2004, the 12 µg/h (actually 12.5 µg/h) formulation was approved as well.
More things that are important you should know about Furanyl Fentanyl
Furanyl Fentanyl is available in three different forms. It can be handy in very fine white to faint white powder. Due to its exceptional form, users can easily smoke or inject it. You can easily purchase Furanyl Fentanyl Powder online and ship within the USA and around the world. Furanyl Fentanyl Powders can also dissolve in water to form a solution. In this form, users can place the Furanyl Fentanyl in a nasal spray with the intention of taking it nasally. Another form of Furanyl Fentanyl Powder is a mixture of heroin. Due to this combination, this form is highly addictive. Users use it for smoking and injection.